Gastric emptying is accelerated in obese type 2 diabetic patients without autonomic neuropathy.
Identifieur interne : 003785 ( Main/Exploration ); précédent : 003784; suivant : 003786Gastric emptying is accelerated in obese type 2 diabetic patients without autonomic neuropathy.
Auteurs : RBID : pubmed:11431601English descriptors
- KwdEn :
- Adult, Blood Glucose (analysis), Blood Glucose (metabolism), Body Mass Index, Diabetes Mellitus (blood), Diabetes Mellitus (physiopathology), Diabetes Mellitus, Type 2 (blood), Diabetes Mellitus, Type 2 (physiopathology), Diabetic Neuropathies, Female, Gastric Emptying (physiology), Hemoglobin A, Glycosylated (analysis), Humans, Indium Radioisotopes (diagnostic use), Male, Middle Aged, Obesity, Patient Selection, Pentetic Acid (diagnostic use), Radiopharmaceuticals (diagnostic use), Reference Values, Technetium Tc 99m Aggregated Albumin (diagnostic use).
- MESH :
- chemical , analysis : Blood Glucose, Hemoglobin A, Glycosylated.
- chemical , diagnostic use : Indium Radioisotopes, Pentetic Acid, Radiopharmaceuticals, Technetium Tc 99m Aggregated Albumin.
- chemical , metabolism : Blood Glucose.
- blood : Diabetes Mellitus, Diabetes Mellitus, Type 2.
- physiology : Gastric Emptying.
- physiopathology : Diabetes Mellitus, Diabetes Mellitus, Type 2.
- Adult, Body Mass Index, Diabetic Neuropathies, Female, Humans, Male, Middle Aged, Obesity, Patient Selection, Reference Values.
Abstract
To clarify the impact of type 2 diabetes mellitus on the gastric emptying rate.
PubMed: 11431601
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Gastric emptying is accelerated in obese type 2 diabetic patients without autonomic neuropathy.</title><author><name sortKey="Bertin, E" uniqKey="Bertin E">E Bertin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Diabetology, CHU Robert Debré, Reims, France. ebertin@chu-reims.fr</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Diabetology, CHU Robert Debré, Reims</wicri:regionArea><placeName><region type="région">Champagne-Ardenne</region><settlement type="city">Reims</settlement></placeName></affiliation></author><author><name sortKey="Schneider, N" uniqKey="Schneider N">N Schneider</name></author><author><name sortKey="Abdelli, N" uniqKey="Abdelli N">N Abdelli</name></author><author><name sortKey="Wampach, H" uniqKey="Wampach H">H Wampach</name></author><author><name sortKey="Cadiot, G" uniqKey="Cadiot G">G Cadiot</name></author><author><name sortKey="Loboguerrero, A" uniqKey="Loboguerrero A">A Loboguerrero</name></author><author><name sortKey="Leutenegger, M" uniqKey="Leutenegger M">M Leutenegger</name></author><author><name sortKey="Liehn, J C" uniqKey="Liehn J">J C Liehn</name></author><author><name sortKey="Thiefin, G" uniqKey="Thiefin G">G Thiefin</name></author></titleStmt><publicationStmt><date when="2001">2001</date><idno type="RBID">pubmed:11431601</idno><idno type="pmid">11431601</idno><idno type="wicri:Area/Main/Corpus">003984</idno><idno type="wicri:Area/Main/Curation">003984</idno><idno type="wicri:Area/Main/Exploration">003785</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Blood Glucose (analysis)</term><term>Blood Glucose (metabolism)</term><term>Body Mass Index</term><term>Diabetes Mellitus (blood)</term><term>Diabetes Mellitus (physiopathology)</term><term>Diabetes Mellitus, Type 2 (blood)</term><term>Diabetes Mellitus, Type 2 (physiopathology)</term><term>Diabetic Neuropathies</term><term>Female</term><term>Gastric Emptying (physiology)</term><term>Hemoglobin A, Glycosylated (analysis)</term><term>Humans</term><term>Indium Radioisotopes (diagnostic use)</term><term>Male</term><term>Middle Aged</term><term>Obesity</term><term>Patient Selection</term><term>Pentetic Acid (diagnostic use)</term><term>Radiopharmaceuticals (diagnostic use)</term><term>Reference Values</term><term>Technetium Tc 99m Aggregated Albumin (diagnostic use)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Blood Glucose</term><term>Hemoglobin A, Glycosylated</term></keywords><keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Indium Radioisotopes</term><term>Pentetic Acid</term><term>Radiopharmaceuticals</term><term>Technetium Tc 99m Aggregated Albumin</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Blood Glucose</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Diabetes Mellitus</term><term>Diabetes Mellitus, Type 2</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Gastric Emptying</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Diabetes Mellitus</term><term>Diabetes Mellitus, Type 2</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Body Mass Index</term><term>Diabetic Neuropathies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Obesity</term><term>Patient Selection</term><term>Reference Values</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To clarify the impact of type 2 diabetes mellitus on the gastric emptying rate.</div></front></TEI><pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">11431601</PMID><DateCreated><Year>2001</Year><Month>06</Month><Day>29</Day></DateCreated><DateCompleted><Year>2001</Year><Month>09</Month><Day>20</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1262-3636</ISSN><JournalIssue CitedMedium="Print"><Volume>27</Volume><Issue>3</Issue><PubDate><Year>2001</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Diabetes & metabolism</Title><ISOAbbreviation>Diabetes Metab.</ISOAbbreviation></Journal><ArticleTitle>Gastric emptying is accelerated in obese type 2 diabetic patients without autonomic neuropathy.</ArticleTitle><Pagination><MedlinePgn>357-64</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To clarify the impact of type 2 diabetes mellitus on the gastric emptying rate.</AbstractText><AbstractText Label="MATERIAL AND METHODS" NlmCategory="METHODS">Using a double-isotope scintigraphic technique, we assessed the gastric emptying of a standard liquid-solid meal in 13 obese type 2 diabetic patients without autonomic neuropathy (age: 47.4 +/- 8.6 yr, body mass index: 33.9 +/- 4.8 kg/m(2), glycaemia: 9.1 +/- 2.6 mmol/l) and in 7 controls with similar sex ratio, age, BMI and body fat distribution.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The half gastric emptying time for the liquid phase was not significantly different between diabetic patients and controls (respectively: 52.7 +/- 14.5 min and 63.1 +/- 15.2 min). However, the half gastric emptying time for the solid phase was significantly shortened in diabetic patients versus controls (respectively 88.8 +/- 23.2 min in diabetic patients and 113.6 +/- 26.9 min in controls; p<0.04). Furthermore, a negative relationship was highlighted between the half gastric emptying time for the solid phase and basal glycaemia (r=-0.65, p<0.02) in diabetic patients. No significant relationship was found between gastric emptying parameters and cardiac autonomic nerve function, insulin or gastrin levels.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Solid gastric emptying is accelerated in obese type 2 diabetic patients without patent autonomic neuropathy when compared to obese non diabetic patients.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bertin</LastName><ForeName>E</ForeName><Initials>E</Initials><Affiliation>Department of Diabetology, CHU Robert Debré, Reims, France. ebertin@chu-reims.fr</Affiliation></Author><Author ValidYN="Y"><LastName>Schneider</LastName><ForeName>N</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Abdelli</LastName><ForeName>N</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Wampach</LastName><ForeName>H</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Cadiot</LastName><ForeName>G</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Loboguerrero</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Leutenegger</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Liehn</LastName><ForeName>J C</ForeName><Initials>JC</Initials></Author><Author ValidYN="Y"><LastName>Thiefin</LastName><ForeName>G</ForeName><Initials>G</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType>Comparative Study</PublicationType><PublicationType>Journal Article</PublicationType><PublicationType>Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>France</Country><MedlineTA>Diabetes Metab</MedlineTA><NlmUniqueID>9607599</NlmUniqueID><ISSNLinking>1262-3636</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Blood Glucose</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Hemoglobin A, Glycosylated</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Indium Radioisotopes</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Radiopharmaceuticals</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>Technetium Tc 99m Aggregated Albumin</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance>technetium Tc 99m nanocolloid</NameOfSubstance></Chemical><Chemical><RegistryNumber>7A314HQM0I</RegistryNumber><NameOfSubstance>Pentetic Acid</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Blood Glucose</DescriptorName><QualifierName MajorTopicYN="N">analysis</QualifierName><QualifierName MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Body Mass Index</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Diabetes Mellitus</DescriptorName><QualifierName MajorTopicYN="N">blood</QualifierName><QualifierName MajorTopicYN="Y">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Diabetes Mellitus, Type 2</DescriptorName><QualifierName MajorTopicYN="N">blood</QualifierName><QualifierName MajorTopicYN="Y">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Diabetic Neuropathies</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Gastric Emptying</DescriptorName><QualifierName MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Hemoglobin A, Glycosylated</DescriptorName><QualifierName MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Indium Radioisotopes</DescriptorName><QualifierName MajorTopicYN="N">diagnostic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="Y">Obesity</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Patient Selection</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Pentetic Acid</DescriptorName><QualifierName MajorTopicYN="N">diagnostic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Radiopharmaceuticals</DescriptorName><QualifierName MajorTopicYN="N">diagnostic use</QualifierName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Reference Values</DescriptorName></MeshHeading><MeshHeading><DescriptorName MajorTopicYN="N">Technetium Tc 99m Aggregated Albumin</DescriptorName><QualifierName MajorTopicYN="N">diagnostic use</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2001</Year><Month>6</Month><Day>30</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2001</Year><Month>9</Month><Day>21</Day><Hour>10</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2001</Year><Month>6</Month><Day>30</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">11431601</ArticleId><ArticleId IdType="pii">MDOI-DM-06-2001-27-3-1262-3636-101019-ART7</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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